Magnetic stimulation in aphasia

Magnetic stimulation in aphasia

  • Estimulación magnética en afasia. Clínica San Vicente

MAGNETIC STIMULATION IN APHASIA

1.-  INTRODUCTION

After suffering a stroke, from the acute post-lesional phase, a reorganization of neural networks that have not been affected is generated, so that the healthy neurons can “learn” functions from the damaged neurons and then replace them, leading to neuronal plasticity or neuroplasticity. Neuroplasticity or neural plasticity is the ability to auto-reorganise nerve tissue.

This phenomenon (neuroplasticity) is determined by genetic factors, patient age, degree of dependency prior to the damaging event, earliness with which neurorehabilitation, social and family support, intercurrent complications, as well as the location, intensity, nature and extent of the brain injury begin.

Most symptoms after stroke are not only due to the injury itself, but due to the hyperactivity registered in the hemisphere intact to the injured hemisphere, which is inhibited.

 On the other hand, TMS (Transcranial Magnetic Stimulation) accelerates neuroplasticity mechanisms, quickly reorganizing brain connections, which leads to greater efficiency of neural networks in the affected area.

 Low frequency (≤ 1 Hz) repetitive TMS (rTMS) applied to the healthy hemisphere reduces diffuse cortical activation, after a stroke, in the primary and secondary motor areas of both brain hemispheres, activating the injured cortical area that had been inhibited and encouraging its excitability and motor recovery. However, low frequency rTMS (≥ 5 Hz) increases cortical excitability and can be applied to produce a neural stimulation of the cortex of the injured hemisphere. Meaning it accelerates neuroplasticity mechanisms, quickly reorganizing brain connections, which leads to greater efficiency of neural networks in the affected area.

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 TMS  has come to be considered a therapeutic reality for neurodegenerative, psychiatric, neurological diseases and other clinical specialties conferring neuroprotective effects that impact positively on the modulation of neuroplasticity, helping the brain in its ability to renew and/or reconnect neural circuits and thus acquire new skills.

TMS in stroke can also be used as a regenerative therapy technique.

With regard to its therapeutic effects in stroke patients, TMS can be focused towards enhancing neuroplasticity, and thus towards each of the symptoms associated with stroke (motor recovery, language and swallowing disorders, depression and perceptual and cognitive impairments).

The basis of this neurorehabilitation therapy is based on the fact that the brain is a dynamic entity adaptable to both internal and external environmental changes.

 TMS is a technique that allows us to act positively on these neural changes in a safe and non-invasive, provided that it is implemented by an experienced team: The intensity of the electromagnetic pulse in the implementation of the TMS is an individual and specific measure for each patient, therefore guidelines and protocols have to be followed, given that there is variability depending on the medical and therapeutic equipment used to apply it.

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2. – WHAT IS APHASIA?

Aphasia is a disorder that affects the ability to express and/or understand language, usually following an injury in the perisylvian region of the left cerebral hemisphere.

In short, aphasia is an impairment acquired in the ability to emit and/or understand language, both oral and written, as well as gestural.

Language is the vehicle of thought. Aphasia disorders almost always involve other functions of the written language (dysgraphia) and reading (alexia).

 The aphasic patients clinic will act according to the location and size of the brain injury, as well as the cerebral capacity of healthy neurons to assume the functions of the injured ones (what we call neural plasticity or neuroplasticity).

 Sometimes, after the harmful event, the organizational changes in the interneuronal brain activity of the affected area and the surrounding healthy regions can recover language capacity. Therefore when patients suffering from aphasia go beyond the acute period of convalescence and are stabilized, they should receive speech therapy in order to help achieve this objective.

 The cause of aphasia is varied: a stroke or cerebral infarction (this is the most common cause), a head injury, an infection of the brain, a brain tumour, dementia, etc.

 The right and left brain hemispheres have different functions with regard to language, the left is more specialized in the lexical and syntactic aspects, and right in the prosodic aspects or “emotional” aspects of language.

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3- WHAT IS TRANSCRANIAL MAGNETIC STIMULATION (TMS)?

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TMS is a non-invasive form of stimulation of the cerebral cortex, and represents a technical tool that extends the range of possibilities for study and research in the field of neuroscience, as well as in the treatment of various diseases and neuropsychiatric disorders. It allows safe, painless and non-invasive stimulation of the nervous tissue (cerebral cortex, spinal cord, central motor pathways and peripheral nerves) as well as the controlled regulation of brain activity.

Fundamentals:

 TMS is based on the principle of electromagnetic induction discovered by Michael Faraday in 1831. An electric current passes through a coil of copper wire encapsulated in a plastic housing, located on the patient’s head. When a pulse of current passes through the stimulation coil, a magnetic field is generated which passes through the scalp and cranial vault undiminished. This magnetic field which is variable over time induces an electric current in the neuronal tissue of the brain, whose volume depends on the shape, size, type and orientation of the coil, the strength (intensity) of the magnetic field and the frequency and duration of the magnetic pulses produced. Thus, TMS might be considered a form of non-invasive electrodeless electrical stimulation by electromagnetic induction.

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This electric current acts on brain cells (neurons) inhibiting or stimulating their effects.

From the therapeutic perspective, there are a lot of studies that show that transcranial magnetic stimulation is effective and can also be considered safe, provided that it is used by a qualified medical team and safety guidelines are met.

 4- CURRENT THERAPEUTIC APPLICATIONS AND USE OF THE TMS:

 Since TMS is a non-invasive, well tolerated technique, with few contraindications, it has become a cutting edge therapy, used to treat various disorders, both psychiatric and neurological (especially in patients with cerebrovascular pathology), and is approved by the Food and Drug Administration of the United States as a treatment of choice when the patient experiences a major depression refractory with conventional drug treatment.

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Its applications are numerous and increasingly broad thanks to research that is emerging every year:

Aphasia: Aphasia, in its various forms, is a common consequence of stroke, especially in the left hemisphere, characterized by impairments in speech, comprehension, reading and writing. Treatment with TMS is more efficient, based on published scientific literature, in patients with motor aphasia (not fluent) or in global forms of aphasia with motor predominance.

Several studies have helped to confirm that stimulation alone improves language disorders in the identification of images, such as in spontaneous speech, and repeatition, nomination and comprehension tests.

 Oropharyngeal dysphagiaAlthough its incidence is 50% in stroke patients, oropharyngeal dysphagia is underestimated and underdiagnosed, constituting a cause of malnutrition and aspiration pneumonia, which increases the mortality rate in these patients (20-30% of post-stroke deaths).

 Oropharyngeal dysphagia produces two types of complications: impairments in swallowing efficiency (causing malnutrition or dehydration) and insecurity swallowing (which can produce aspiration pneumonia). Dysphagia after a stroke is a result of the damage to the dominant motor cortex.

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5.- OUTLINE OF THE TREATMENT

 Before starting the first rTMS session, a medical visit is carried out to verify that the patient presents no contraindication and the patient is able to participate in the treatment. A speech therapy assessment is also performed before and after treatment, and subsequent follow-up visits are made to assess the response to this type of combined neurorehabilitation therapy.

 APHASIA TREATMENT PLAN: The treatment protocol for aphasia that takes place at the San Vicente Clinic is based on the protocol developed by the Berenson-Allen Center for Noninvasive Brain Stimulation (CNBS) at Beth Israel Deaconess Medical Center and Harvard Medical School, whose scientific support is based on research work carried out mainly by Margaret Naeser and her colleagues.

 It consists of 10 sessions of rTMS (a daily session for 10 working days of two weeks) of 20 continual minutes of intensive speech therapy (approximately 2 hours daily).

 DYSPHAGIA TREATMENT PLAN: The application of the stimulation is applied 10 minutes a day for 2 weeks, on the contralesional motor cortex, having demonstrated the improvement in swallowing and decreased risk of aspiration after treatment.

 6.- SIDE EFFECTS

 TMS is a safe technique provided that safety guidelines are followed. Some patients undergoing this cortical stimulation may experience side effects after application, which might be considered mild and transient, such as cephalic or cervical pain; and in the rare situation of persistence, this is mitigated by taking common painkillers.

 Moreover, the risk of seizures during TMS is very low and it has not been shown that TMS increases the risk of seizures in patients with controlled epilepsy, once the stimulation session has ended.

 7.- CONTRAINDICATIONS

 The main relative contraindications that TMS has are: women who are pregnant and children under six.

 The following is a list of patients that have absolute contraindications: those with pacemakers, deep brain stimulation electrodes, personal electronic devices (drug infusion pumps) or intracranial metallic elements (metal plates, wires, screws, heart valves or ventriculoperitoneal bypass, cochlear implants, etc.). Nor should treatment be performed on patients with uncontrolled epilepsy. Before starting treatment a doctor will evaluate each case individually, to rule out any contraindications.

Símil gráfico de precaución ante contraindicaciones terapéuticas.

8.- CONCLUSIONS

  • TMS has proven to be a cutting-edge technical ally, safe and effective in treating the deficits that may arise after a stroke, as well as in terms of safety, it is innocuous to the patient. Likewise, TMS has proven to be especially valuable in helping to promote brain regeneration by means of the neuroplasticity mechanism.
  • Excitatory and inhibitory electromagnetic pulses applied in the ipsilateral or contralateral cerebral hemisphere to the lesion, as well as the transcallosal area in order to modulate communication between the two brain hemispheres (depending on the desired effect), offer us the possibility of optimizing functional brain activity by inducing changes in interhemispheric connectivity, as well as achieving recovery of the damaged brain area in less time.
  • The various studies conducted in the field of TMS have confirmed the improvement of motor disorders, aphasia, spasticity, oropharyngeal dysphagia and perceptual and cognitive difficulties that occur in patients with a stroke.

Símil gráfico de las conclusiones actuales a considerar de la EMT.

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  • Neurophysiology and ultrasound services
  • Neuropsychology
  • Clinical psychology
  • Child physiotherapy: Vojta method
  • Occupational Therapy
  • Speech Therapy
  • Nursing

GENERAL OBJECTIVES

  • Evaluation, assessment and diagnosis of neuropsychological and psychopathological disorders in adolescents and children.
  • Development, implementation and evaluation of intervention and rehabilitation treatment plans after stroke or traumatic injury.
  • Detection, identification and localization of brain and orthopaedic injuries.
  • Study and detection of simulation.
  • Monitoring of cognitive behavioural progress during the therapeutic process.
  • Speech therapy and psychological expert opinions.
  • Evaluation of the reintegration into education.
  • Evaluation of mental retardation.
  • Assessment of special educational needs.
  • Medico-legal assessments for accident compensation

REHABILITATION PROGRAMMES

Intensive rehabilitation programmes in:

  • Disorders of cognitive function.
  • Learning problems.
  • Mental deficiency.
  • Language disorder.
  • Swallowing disorder
  • Disorders of communication and social interaction.
  • Motor conduct disorder
  • Laterality problems.
  • Psychomotor instability.
  • Behavioural disorders.
  • Oppositional, defiant, hostile and aggressive behaviour.
  • Phobias and fears.
  • Obsessive behaviours and rituals.
  • Hysterical behaviour.
  • Affective disorders.
  • Anguish and anxiety.
  • Bladder/bowel control problems.
  • Movement disorders, hemiplegia and tetraparesis.
  • Rehabilitation of multiple injuries from falls, car accidents or sports

SCALES USED IN ASSESSING NEUROPSYCHOLOGICAL DEFICITS SPECIFIC TO THE CHILD POPULATION

  • Wechsler Intelligence Scale for Preschool and Primary School (WPPSI): set of tests that explore certain cognitive functions and provides verbal, manipulative and total IQs, from 4 years to 6 ½ years of age.
  • Wechsler Intelligence Scale for Children – Revised: set of tests that explore certain cognitive functions and provides verbal, manipulative and total IQs, in children from 6 years to 16 years of age.
  • Neuropsychological Diagnosis for Children (Luria-DNI) studies the different neuropsychological processes in the child patient, being very sensitive to the slightest impairment.
  • Family Drawing Test: projective test for the diagnosis of childhood emotion which explores the conflicting experiences of the child.
  • Raven’s Progressive Matrices Test.
  • Rey complex figure.
  • Benton Visual Retention Test.
  • BOSTON aphasia assessment and other related disorders.
  • Harris handedness test.
  • Symbol digit modalities test (SDMT).
  • Porteus Maze Test.
  • Stroop Colour and Word Test
  • TALE literacy analysis test.
  • Thematic Apperception Test (adult and child, TAT, CAR-A and CAT-H).
  • Machover draw-a-person test.
  • DÜSS fables.
  • Test ABC by Filho.
  • Token test.
  • Picq and Vayer psychomotor examination.

Physiotherapy Unit

From our Physiotherapy Unit we work on the prevention, cure and palliation of various musculoskeletal disorders of the nervous and respiratory system caused by various injuries, in order to achieve the highest degree of functional capacity and possible independence for the patient.

We have professionals specializing in neurological physiotherapy, as well as respiratory and orthopaedic physiotherapy. These use the Bobath Concept, the Perfetti Method and tools such as dry needling and Kinesio Taping for neurological disorders, as well as the different techniques for respiratory physiotherapy in order to improve respiratory function; and manual therapy and electrotherapy techniques for musculoskeletal injuries.

Psychiatry Unit

ROLE OF THE PSYCHIATRIST IN NEUROREHABILITATION

The patient with a brain injury presents syndromes that combine cognitive disorders (memory, language, reasoning, attention, etc.) with emotional and behavioural disorders. In fact, it is very rare that they only suffer from motor impairment (inability to walk, paralysis, etc.). Our obligation is to describe in detail these changes in the assessment of patients. That is why the information provided by their families and people who know them well is essential since on occasions certain changes could go unnoticed in a medical interview. On the other hand, in order to understand the cognitive situation we have with the invaluable help of the assessment of the neuropsychologist. And for the diagnosis and treatment of these disorders we have the presence of the psychiatrist. But not a consultant psychiatrist that examines the patient on only one occasion and where if considered appropriate, a treatment treatment is indicated, what we have is a “bedside” psychiatrist.  This person is with the patient day-to-day, which is essential to understanding the patient and their progress. Another function of the psychiatrist can be the modular, the interaction of the interdisciplinary team with families. People can feel support and harmony from simple active, empathetic listening.

People with brain damage may have changes in mood and emotional lability, with a tendency to cry or laugh for no apparent reason. Quite often depression can occur, which should be treated pharmacologically, because otherwise it may stall the overall progression of the patient. In fact, if there is no improvement in a patient, without the justification of organic cause or elapsed time, the presence of depression should be suspected. Disinhibition, lack of self-control or “slow-down” is also frequent, which can lead patients to say anything that they think, without considering whether it is appropriate or not, or to an action, without anticipating the consequences of what they are doing, with impulse prevailing over respect for social standards. Anger, irritability, or even aggressiveness may occur. But also the opposite is the case, with the occurrence of apathy. On other occasions, a degree of impatience, immaturity, puerility or egocentric behaviours may dominate, with the patient, in general, lacking empathy. They want something and they want it immediately, with no capacity to wait. The way of being of the person concerned, their personality, can change after brain damage. This may result in exacerbation and exaggeration from the previous characteristics of the patient, in their way of being, even to the point of radical or extreme change that makes the familiar say things such as “I have a stranger at home”, “I don’t recognize him”.

In many cases, psychopharmacology can be useful to treat certain impairments that may arise. For example, it may be helpful in insomnia, emotional lability or depression. In fact, a high percentage of patients benefit from the psychopharmacological treatments. The specialist psychiatrist in brain damage will know the medications that can cause iatrogenic complications in patients suffering from brain damage and which, therefore, should not be used. The specialist psychiatrist will also indicate, if considered appropriate, and once the family and patient have been informed, whether to use certain techniques such as Transcranial Magnetic Stimulation.

Psychiatry tries to understand the psychological suffering of the individual, and how it spreads to the family, therefore the interrelationship between them and the brain damage is necessary and unavoidable.

Therefore, upon admission the psychiatrist will perform a psychopathological examination on the patient and will undertake a psychopathological interview with the family. Hence, extract enough data to be able to relay the situation and mode of action to the team. On occasions, an indication of physical containment will be necessary (due to not being aware of disease and the existence of risk to one’s person or third parties, aggressiveness, etc.). To have a real understanding of the cognitive and affective-behavioural situation, it is essential, in addition to the data provided by neuropsychology, to observe the patient outside of the office, the way they act and interact with different people in everyday situations and in different spaces. Their condition is transferred to the team during clinical sessions, and depending on these sessions, and in accordance with the therapists, the objectives are planned and treatment is indicated, where considered appropriate.

Throughout the time that the patient is undergoing neurorehabilitation therapy they will be reviewed daily. A sketch is made of their mental state and behaviour, their oscillations or changes, and in line with this the appropriate action is taken. According to their progress, the objectives to be achieved are jointly re-established with the rest of the interdisciplinary team. The family is essential in this process and they continue to provide information on these matters.

When it gets close to hospital discharge, a report will be drafted in which the cognitive-behavioural and emotional situation will be outlined, as well as the improvements achieved and current status, along with drug treatment, if required, all of which will be reported to the family.

Language disorders: APHASIAS

APHASIAS

Aphasia are expressive and/or receptive language disorders that occur due to brain injury. With few exceptions, they are also presented with impaired reading and writing. They are very common disorders in people who suffer a stroke and an unknown pathology for much of today’s society.

Aphasia is probably the biggest sequela or limitation, from a personal, social and economic point of view, caused by brain damage. Therefore, adaptation to a sudden loss of language skills involves numerous emotional and cognitive adjustments, since it is through language that people channel their thoughts and communicate with their environment.

Thus, rehabilitation from aphasia should meet the objectives of increasing the language capabilities of the patient and, at the same time, help them cope with their new circumstances, reworking their self-confidence. The sooner treatment begins, and the more frequent the sessions, the better the recovery will be, especially during the first month after injury and during the next six months. Subsequently, the rate of progress decreases, although it does not stop.

However, it is difficult to accurately predict the effect of rehabilitation due to the magnitude of factors involved, including the specifics of the injury (type, location, etiology, size, etc.) and factors inherent to the patient (age, handedness, sex, etc.), there are also other factors that can enhance the treatment such as prior intellectual and educational level, language level, general health and motivation to recovery, among other things.

Conversely, there may also be other associated factors that hamper the recovery such as alterations in the level of consciousness, sensory and motor deficits, epilepsy or depression. Anosognosia or ignorance on the part of the patient that presents disorders is a major obstacle that makes rehabilitation infeasible, the patient must therefore overcome this before having access to the rehabilitation. Patients with anosognosia do not perceive that they present difficulties in expressing or understanding what you say, so they speak using “strange” words in a completely natural way and may find it strange if the other person does not understand them.

There are various clinical types of aphasia, according to the predominance of the impairments in one or other of the aspects of language (expression, comprehension, repetition and designation) and preserved linguistic mechanisms.

  1. Total or global aphasia: the most severe form of aphasia as a result of massive destruction in the areas concerned with language. It is characterized by significant speech and verbal comprehension impairment. Often the patient presents silence or always emits the same word (stereotypy). Repetition is null. Patients with this type of aphasia may have an attitude of indifference to the environment without communicative intent, looking strangely when you try to interact with them. They cannot speak and cannot understand anything, remaining expressionless and oblivious to what is happening around them.

When understanding improves, but without reaching the levels characteristic of Broca’s aphasia, it is referred to as mixed-motor aphasia. In this case, the patient cannot express themselves, at least not without some effort, but is only able to recite references to time (days of the week, months of the year, etc.) or basic numbers, as well as understand familiar words and everyday expressions such as greetings.

  1. Motor aphasia or Broca’s aphasia: This is characterized by non-fluid and decreased verbal expression, struggling to speak, reduced sentences, abnormal prosody and suppression of grammatical links (agrammatism). The capacity to repeat is altered, as well as the evocation of names of objects or figures (anomie). The comprehension of spoken language is always better than the production and may present some difficulties in understanding more elaborate syntactic relations. For example, the patient may say a word and understand the majority of things that you say to them. Writing and reading are also often flawed, with numerous errors in spelling and the omission of letters.
  2. Receptive aphasia or Wernicke’s aphasia: This is characterized by a predominance of comprehension disorders, with normal articulation and fluency in the majority of cases. Verbal expression is usually increased, with some degree of excitement, and an ignorance of the problem on the part of the patient. Although oral production is effortless, with good articulation and prosody, the unintelligible words predominate (aphasic transformations or paraphasia), leading to jargon that is difficult to understand and that is void of content. In cases where no excessive expression occurs (logorrhea), the lack of words is emphasised (anomie). The capacity for repetition and designation is also affected. Comprehension disorder is the most significant, albeit with varying intensity depending on the severity of the injury. For example, the patient does not understands what they are told very well, although they can express themselves, it is difficult to understand due to the use of “strange” or inappropriate words, similar to a foreign language, making it difficult to hold a conversation, reading and writing are also impaired. Although there is an ability to write, these patients express themselves in writing in the same way as they speak, therefore their writing is often difficult to understand.
  3. Conduction aphasia: characterized by fluent expressive language, with some anomie and paraphasia and an impaired ability to repeat. Patients may have difficulty understanding more complex material. In this case, patients may speak and understand relatively normally, but with some pauses when speaking due to not being able to find the right word, or they may replace the word with another that does not correspond, presenting greater difficulty regarding repetition. Reading is also greatly impaired, while writing is preserved, albeit with many mistakes during dictation, and it is spontaneous.
  4. Anomic or nominal aphasia: is characterized by fluent expressive language, with normal articulation and structure, but with difficulty in evoking words (anomie). Circumlocutional verbal expression can appear (describing a word that you cannot remember) and general words (they use the same word to communicate). Moreover, anomic deficit can appear in spontaneous speech only, it being almost normal in naming an image. For example, these patients have a sense of knowing what they mean or “they have the word on the tip of their tongue”, but fail to be able to say it, so they explain the characteristics or use of the object that they are trying to name. Although understanding is preserved, they may have difficulties in more elaborate tasks. In reading and writing some errors may occur, difficulty finding the right word when writing being more evident.
  5. Transcortical motor aphasia: This is characterized by very small spontaneous expressive language (not fluent). The expression is made with effort, and is slow and brief. The designation of images is impaired, while the capacity for repetition is better. Comprehension can be relatively preserved. These patients speak very little and with effort, but are able to repeat much better. They may also have reduced writing capacity, while oral reading and reading comprehension are preserved, although they may be dissociated, i.e., do not usually understand what they read. If the picture improve progression to an anomic aphasia may be possible.
  6. Transcortical sensory aphasia: characterized by a dissociation between a good capacity for repetition and a defect in the comprehension of words that the patient can repeat, i.e., patients do not understand what they repeat. The verbal expression is fluent in the form of jargon with a prevalence of echolalia (repeating words that are heard). Oral comprehension is usually highly impaired. These patients can repeat very well, but are not able to understand what they repeat. Reading ability may be affected to different degrees and reading comprehension is usually severely impaired. Written expression also appears as jargon that is difficult to understand, i.e., patients write as they speak.
  7. Mixed transcortical aphasia: This is characterized by significant speech and verbal comprehension impairment. The verbal expression is reduced to echolalia and there is no capacity to describe images. In this case, patients cannot express or understand well, but are able to repeat, recite, complete words and phrases, etc. Both reading and writing and reading comprehension are highly impaired.

The different clinical types of aphasia described are the most common and may progress throughout the treatment, going from one set of circumstances to another less serious set of circumstances depending on the improvement achieved.

Speech disorders: DYSARTHRIA

DYSARTHRIA

Speech is one of the most complex behaviours developed by humans. In order for oral production to be performed normally it is necessary to control breathing and the muscles of the larynx, pharynx, palate, tongue and lips.

Dysarthria can be defined as a change in speech articulation due to lesions in the central nervous system as well as diseases of the nerves or muscles responsible for speech.

These impairments in articulation are manifested by omission, substitution, addition or distortion of one or more sounds, affecting the intelligibility of verbal expression. Moreover, these impairments are coupled with the difficulty in moving the mouth parts to perform any activity as sucking or blowing. The most extreme and severe dysarthria case would be anarthria or the inability to properly articulate the sounds speech (phonemes).

The assessment of dysarthria must be meticulous, since similar symptoms can result from very different disorders, both the speech assessment and the alteration of the muscles involved in breathing must be included, the larynx, soft palate, tongue, lips and jaw. In patients with dysarthria, movements of the speech muscles may be impaired with respect to strength, directionality, amplitude, time or resistance.

Dysarthria can cause paralysis, weakness and lack of coordination of the oral musculature, and can be identified by six different types based on the location of the lesion in different areas of the Central Nervous System:

  1. Dysarthria due to lesions in the extrapyramidal system: consisting of gray subcortical nuclei responsible for regulating muscle tone necessary for maintaining and changing posture, it organizes the movements associated with walking and facilitates automation in voluntary acts that require dexterity. Lesions in the extrapyramidal system can cause two types of dysarthria: 1) Hypokinetic: characterized by slow, restricted and stiff movements, repetitive movements in the speech muscles, a weak voice with defective articulation and lack of inflection, short sentences, lack of flexibility and control of the laryngeal muscles, tonal monotony and variability in the articulatory rate (Parkinson’s desease) and 2) Hyperkinetic: characterized by the possible impairment, successively or simultaneously, of all basic motor functions (breathing, phonation, resonance and articulation), it is impossible to predict their occurrence over time. Among the most significant disorders are:
  2. Ataxic dysarthria: this is due to lesions in the cerebellum, the organ that regulates the strength, speed, duration and direction of movements caused in other motor systems, causing hypotonia of the affected muscles, direction impairment, duration and intensity of movements, as well as slow and inappropriate force, possible irregular eye movements, impaired phonation with a voice that is raspy, monotonous and that has little change in intensity, distorted speech articulation and impairment to voice prosody, with an emphasis on certain syllables.
  3. Spastic dysarthria: this is due to damage to direct or indirect activation pathways from the cortex to the brain stem and spinal cord, which can be caused by stroke, head injury, multiple sclerosis, encephalitis, extensive tumours or degenerative diseases. The lesions to these upper motor neuromas cause weakness and spasticity on one side of the body, in the distal limb muscles, tongue and lips, resistance to passive movement of a muscle group, exaggerated muscle stretch reflexes, presence of pathological reflexes such as raising the big toe away from the other toes to stimulate the foot (Babinski sign), impaired breathing and phonation, low monotone and hoarse voice, articulation difficulties and slow speech, production of short sentences with tonal or breathing interruptions, and impaired emotional control with the sudden onset of excessive crying or laughing without any reason.
  4. Flaccid dysarthria: It is due to damage to the neurons of the cranial nerves or spinal cord caused by infections, cerebrovascular accidents and degenerative processes or congenital diseases. Also the cranial or spinal nerves can be affected by trauma, tumours, toxins, inflammatory processes and autoimmune, metabolic or deficiency diseases. Damage to any component of this lower motor unit involves the impairment of the voluntary, automatic and reflex movement, producing flaccidity and paralysis with decreased muscle reflexes, atrophy of the muscle fibres, weakness when exercising the eye and neck muscles, possible breathing impairment, impairment of the tongue and palate movement, decrease in the gag reflex, difficulty in swallowing, weakness of the vocal cords, and the palate and larynx, a hoarse voice with low intensity, hypernasality and distorted articulation of the consonants.
  • Choreas: Disease of the nervous system characterized by involuntary movements and irregularities, slow or fast, of one or more of the muscles. The muscle tone is low and there are impairments in the coordination. These patients have slurred speech, vocal distortion, use short sentences, irregular speech and prosody impairment.
  • Athetosis: is a neurological disorder characterized by involuntary and slow movements in the joint, frequent breathing and phonation problems, a raspy voice, slurred and monotone speech.
  • Tremor: This is a rhythmic form of abnormal movement that sometimes causes interruptions to the emission of the voice.
  • Dystonia: This is an abnormal, involuntary movement, that is slow and sustained, and includes changes in prosody, decreased pitch, audible breaths and voice tremors.

5. Mixed dysarthria: This is the most complex form of dysarthria, in which dysfunction of speech is the result of the combination of the characteristics of the motor systems involved, as in the case of tumours, inflammation, trauma, stroke, degenerative or demyelinating diseases (multiple sclerosis).

The speech therapy will be aimed at correcting defects in the articulatory production of words, either as a result of omission, replacement or distortion of sounds, to improve speech articulation and modify symptoms that significantly influence both the intelligibility of speech and the communicative faculty of the person.

To modify the symptoms presented by a patient it is necessary to intervene in several fundamental fields, such as posture, muscle tone and strength, respiratory mechanics, laryngeal deficiencies during phonation, resonance or excessive hypernasality, as well as areas covering defects in the articulation and impairment of prosody.

  

Voice disorders: DYSPHONIA

DYSPHONIA

The voice is a sound produced by the larynx from pulmonary exhaled air, which is then amplified and reinforced by resonant cavities (pharynx, nasal cavity, oral cavity and the lips). But, in addition, the voice not only reflects but is influenced by the different moods of the person, their personality, health, etc.

The brain governs the implementation of the vocal instrument and directs the execution of the muscle activity involved (rib cage, lungs, vocal cords and resonators).

Dysphonia is the alteration of some of the acoustic qualities of the voice (intensity, pitch, timbre and duration) as a consequence of an organic disorder or improper use of the voice (functional) and can be permanent or temporary. Therefore, aphonia would be the total loss of the voice.

The etiology of speech disorders may be organic, physiological, psychological or environmental, and there are some factors that determine the appearance or duration of such alterations, and even the worsening thereof, such as respiratory diseases (laryngitis, chronic bronchitis, asthma, vegetations, etc.), laryngeal malformations, surgery, laryngeal trauma, respiratory use and improper speech, behavioural characteristics, the family and social environment, and hearing impairment, among other things.

Determining how and to what degree a voice is pathological is not always easy, because there are multiple factors that directly influence the estimation (affective and emotional circumstances, cultural, age, gender, professional standards, self assessment of one’s own voice, etc.) . Therefore, in order to accurately diagnose vocal pathology it is necessary to conduct a comprehensive and thorough study, which includes, in addition to the data on family and personal history, and the history of the disease, an organic exploration of the pharynx, larynx and resonant cavities, a functional examination of the posture, respiratory phonological coordination, vocal sound and maximum phonation and exhalation time, laryngeal function testing by way of laryngostroboscopy or fibroscopy, and an acoustic voice analysis of fundamental frequency, tonal extent, intensity and phonetogram.

Dysphonia can be classified according to three criteria:

  1. Quantitative
  • Aphonia: Total loss of voice.
  • Dysphonia voice alteration in any of its qualities.
  1. Location
  • Laryngophony: Dysphonia located in the larynx, causing bad voice projection (inappropriate tone), vowel hoarseness (strong voice, no timbre and too deep), functional laryngitis (inflammatory processes due to prolonged shouting) and phonasthenia or vocal fatigue (weak shallow voice with no timbre).
  • Rhinophonia: changes in the resonance or nasalization of phonation. This can be:

. Open rhinophonia: the air escapes through the nose during phonation.

. Closed rhinophonia: nasal obstruction that prevents the passage of air through the nostrils.

  1. Etiology
  • Organic dysphonia: caused by lesions in the phonation organs due to causes that are congenital (brain lesions, malformations, paralysis, endocrine factors, etc.), inflammatory (acute and chronic laryngitis) and traumatic (injury wounds, burns, radiation therapy, surgery, etc.).
  • Functional dysphonia: produced by altered vocal attitude that can be complicated by organic lesions of the larynx caused by vocal strain (nodules) or transient organic disorders (laryngitis). These are triggered by acute laryngitis, injuries and allergies, psychological factors, systemic diseases, etc. Predisposing factors to speaking or singing, personal psychological characteristics, consumption of tobacco and alcohol, chronic ENT conditions, poor audio-phonatory control, poor vocal technique, exposure to excessive noise, dust, irritating vapours, etc.

According to the alteration of the vocal attitude and how the patient compensates, one can distinguish between two types of functional dysphonia:

. Hypertonic or hyperkinetic: Excessive tension of the vocal cords during phonation with stress behaviour.

. Hypokinetic or hypotonic: the vocal cords are not completely closed due to lack of muscle tension, with compensation from the adjacent structures.

In the case of functional dysphonia, vocal effort behaviour can lead to an objective laryngeal alteration, known as functional laringopathies, alterations of the mucosa of the vocal fold caused by a vocal behaviour impairment, causing the formation of nodules and polyps.

In general, organic dysphonia requires surgery and then rehabilitation, whereas functional dysphonia requires speech therapy, although, depending on the case, they may require surgery or medication.

The speech therapy intervention for speech disorders is aimed at restoring proper posture and proper breathing mechanics, reduce muscle tension and eliminate laryngeal effort, as well as adapt the cavity resonance to the sound emitted from the larynx.

At the beginning of the vocal therapy detailed information must be provided to patients, as appropriate, on proper vocal hygiene aimed at reducing vocal aggression and carrying out active prevention, providing advice on reducing toxic habits and predisposing factors (dry, cold or very hot environments, sudden temperature changes, etc.), not using the voice over long periods, properly treating impairments and infections of the upper airways, maintaining a lifestyle that is as healthy as possible, using the voice at a moderate level, etc.

The vocal therapy consists of restoring a proper postural attitude to get the best voice with the least possible effort, relaxation exercises to reduce muscle tension, breathing exercises designed to lengthen phonation, regulation of breathing, an increase or decrease in the volume of the voice and correct breathing and restoration of the impaired sound qualities (intensity, duration, pitch and timbre).

Duties of the Social Worker

The figure of the social worker in the field of health and brain damage is relatively new. It came about due to the latent needs of patients; not only to rehabilitate the psychological or motor aspect but also the social aspect.

The first moments of brain damage for the family are very difficult to manage, because they prioritize the state of the patient over what will happen next, the social worker dedicated to Acquired Brain Injury deals with the subacute phase in which the patient and the family are highly involved in rehabilitation. Rehabilitation of all damaged aspects in which all professionals are involved in a multidisciplinary manner in coordination to achieve substantial improvement.

The figure of the social worker focuses on:

Initial phase:

–          Reception of cases to assess the family social structure, the support that the patient receives and the financial resources available to them.

–          Advice on the resources and support that they can manage (Law on dependency, disability, work incapacity, etc.).

During treatment:

–          Link between families and medical staff and professionals from the clinic to achieve better communication and understanding between them.

–          Advice on technical aids necessary for each patient based on economic resources.

–          Find resources upon discharge and perform coordination with social services in the area, and social work of the referral hospital.

–          Attention to families, guiding and helping them to face the new social situation.

Upon hospital discharge:

–         Support for families at the return-home phase,

–          Prevent over-burdening the family, accompanying them in solving social problems generated during the recovery process.

–          Advice on normalization and rehabilitation of the daily life of the family nucleus.

Duties of the Neuropsychologist

PETITION TO INTERVENE

Initially, the intervention by the Neuropsychologist may be requested for the purpose of evaluation, assessment and diagnosis of higher psychological functions and affective-behavioural condition, in order to understand the problem with the patient, as well as its cause and implications.

More specifically, the purpose of the assessment may be aimed at the detection and localization of brain lesions, in cases such as low-severity brain disorders, the beginning of degenerative processes, minimal brain dysfunction, etc.

The differential diagnosis may also be an objective of neuropsychological assessment, i.e. discriminating whether changes that the patient presents have an organic base, or conversely are functional, such as the differential diagnosis of depression/dementia.

Moreover, the evaluation process can be directed towards the study and detection of simulation in the judicial proceedings, in which there may doubt over the veracity of the disorder and/or exaggeration of possible symptoms.

In the same judiciary scope, the valuation may go to the completion of forensic neuropsychological appraisals, whose purpose is to objectify and determine, with the highest degree of accuracy, possible difficulties and their implications for the life of the person. That is to say, the consequences associated with neurological disorders, in their bio-psycho-social and labour dimension, are measured.

Regarding the work sphere, the assessment of psychological functions after brain injury is performed in order to consider possible reintegration into the workplace.

Furthermore, with regard to the child population, the study may be directed to more specific issues such as the progress of mental retardation and assessment of special educational needs.

WHAT DOES THE NEUROPSYCHOLOGIST EVALUATE AND ASSESS?

Basically we can divide the field of study of the neuropsychologist into two: higher psychological functions and the effects, emotions and behaviour.

Higher psychological functions are those cognitive abilities that allow us to face, effectively and efficiently, the demands of everyday life to which we are exposed through people throughout our lives, and thus we can distinguish the following:

–       Orientation: this covers 4 dimensions. Personal, in which the most essential and close information to the person is sought (name, age, date of birth, marital status, etc.). Temporal, in which the time parameters are valued (day of the week, day of the month, month and year). Spacial, the degree of knowledge that the person has on your location is looked at (place where they are located, city, etc.). Situational, explores the degree of knowledge that the person has about their present situation (what’s happened, where, and why is the person in the hospital, etc.).

–       AttentionThis is the basic mechanism underlying all cognitive processes that enables the person to focus on any proposed activity, without losing the its progress, allowing them to be kept immersed for a period in a given activity (studying, driving, reading a book, watching television, following a conversation, performing a routine domestic or household task, etc.).

–       Hemi-spacial neglect: This is the difficulty to address and respond to stimuli within a hemispacial and hemibody area, contralateral to the lesion.

–       The speed of information processing and execution: The speed with which our brain processes information and can issue a response. Any activity that we carry out requires an adequate speed in order to function effectively. After a brain injury, the brain slows down, needing more time to perform any activity (talking, answering, thinking, writing, etc.).

–       Language: This is the faculty that allows us to communicate with each other, and can be considered as an expressive or comprehensive mode, by allowing us to understand the messages conveyed and in turn allowing us to issue our own messages. That is, it is the basis of personal relationships and social communication. Also, language is a tool for intellectual activity (thinking, memorizing, representing reality, etc.) and for the organization and regulation of mental processes (planning, scheduling, etc.). Language can be impaired in different ways, each forming a characteristic syndrome (aphasia).

–       Reading and writing are special forms of comprehensive and expressive language.  Therefore, people with language impairment (aphasia) will have difficulty expressing or understanding written instructions and messages. We can also assess changes in reading and writing independently and without language impairment (dyslexia and agraphia).

–       Arithmetic skill is the ability to identify and understand numeric values and perform arithmetic operations (money management, accounts and problems.). This can also be affected as part of language disorders, but impairments may also occur independently (acalculia).

–       Memory is one of the most important fields of neuropsychological investigation. The type of problem will vary depending on the brain structures affected. Some people have generalized impairments, others more specific to retaining verbal information (names, text, etc.), as well as impairments in retaining visual information (images, video, physical spaces, etc.), other examples include problems with immediate information (repeating a phone number), or the ability to retain the temporal order of events, etc. Memory is largely what makes us different as people. “We are what our memory is”, from the moment we are born we accumulate experiences and memories, and when they disappear through injury, we erase all of our personal history. Difficulties can be rendered visible in daily life, presenting problems in retaining information managed by the person, directly or indirectly, (what he has done the previous day, who he has called on the phone, conversations, movies, reading newspapers and books, and can even lead to repetition due to having forgotten that the subject has already been mentioned, etc.), as well as prospective memory (what to do tomorrow, what to buy, what food do I have to make today, etc.). Similarly, memory problems may lead to the inability to recognize familiar faces and people (you can mistake the wife and children for strangers), or the immediate area in which we live (become disoriented and lost in a familiar place).

–       Executive functions are evaluated rigorously in neuropsychological investigation, constituting the cognitive capacities involved in the initiation, planning, programming, controlling and regulation of all cognitive processes and behaviour. Allow the proper handling of the information that we receive, which allows us to understand and efficiently integrate with the demands of daily life, acting in a planned and programmed manner, anticipating the consequences of our behaviour (preparing food, household activities, shopping, etc.).

–       The superior visual functions will be needed to handle all the information, in visual form, that we see daily; we distinguish between the following three groups:

–       Visuoperceptual functions:

o    Problems in visual analysis and synthesis (discriminating the differences between similar images, inferring an image from an element).

o    Problems in recognizing objects and pictures (visual agnosia), where the patient does not know what a particular and known object or drawing is.

o    Difficulties in facial recognition (the patient does not recognize faces, even those with whom they are closest).

–       Visuospacial functions:

o    Problems locating a given point in space and tracking it with the eye.

o    Problems appreciating the distance from a given a point in space.

o    Difficulty recognizing the same image or object in a different position.

o    Problems or topographical orientation (people becoming spatially disoriented and may even become lost).

o    Hemi-spacial visual neglect (difficulty responding to stimulation from one side of a spacial area, either the right or the left).

–       Visuoconstructive functions:

o   Problems assembling or joining (doing puzzles, building figures with parts, etc.).

o    Problems copying or drawing.

–       The motor functions are explored through the study of motor skills, handedness, left/right orientation, motor coordination and performing movements and gestures (praxis) with hands (complex) and the mouth and face (orofacial).

–       Perception and reproduction of rhythmic structures consists of the imitation and production of sequences and rhythms, the impairment of which is closely related to disorders such as dyslexia or aphasia.

–       Examination of higher cutaneous and kinesthetic functions is necessary for studying skin, muscle and joint sensations. These are of great importance in examining the brain areas that receive such information, valuing also touch, discrimination and tactile sensitivity.

–       IQ or Intellectual Quotient (IQ), is a means of intelligence scales, by which we can obtain the general intellectual performance of the individual, as a global measure of cognitive functionality.

From an emotional-behavioural point of view, the following problems are treated:

– Apathy, indifference and demotivation.

– Lack of initiative and not completing activities.

– Impulsiveness.

– Lack of awareness of disease and deficits (anosognosia).

– Confabulation (memory gaps that the patient fills with fantasy and that have a behavioural impact).

– Irritability and aggressiveness.

– Inappropriate sexual conduct.

– Disinhibition.

– Depersonalization (feeling of being separated from one’s body and mental processes).

– Derealization (feeling that one’s surroundings are not real and are strange, like a dream).

– Childish and immature attitude.

– Egocentrism.

– Emotional lability (rapid mood changes).

– Difficulty with emotional expression (aprosodia).

– Difficulty controlling and regulating behaviour.

– Deficits in social skills.

– Suspiciousness or paranoid ideation.

– Changes in thought content (delusions, overvalued, obsessive).

– Changes in the course of thought (concretism, stiffness, prolix thought, tirelessness).

– Perceptual changes (hallucinations).

– Mood disorders.

From the psychopathological point of view disorders that may or may not be associated with brain injury are measured:

– Anxiety disorders.

▪ Specific phobias.

▪ Social phobia.

▪ Agoraphobia.

▪ Panic disorder.

▪ Obsessive compulsive disorders.

▪ Post traumatic stress disorder.

▪ Generalized anxiety.

– Sexual dysfunctions.

▪ Hypoactive sexual desire.

▪ Sexual aversion disorder.

▪ Erection disorder in men and arousal disorder in women.

▪ Ejaculation disorder.

▪ Female orgasmic disorder.

▪ Problems and couple therapy.

– Somatoform disorders.

▪ Hypochondria.

▪ Body dysmorphic disorder.

– Mood disorder.

▪ Depression.

▪ Bipolar disorders.

– Factitious disorder (intentional production or feigning of symptoms).

– Personality disorders.

Specifically assessed in the child population:

– Encephalopathy and cerebral palsy.

– Disorders of cognitive function.

▪ Learning disabilities (reading, writing and arithmetic).

▪ Mental deficiency.

– Language disorder.

– Disorders of communication and social interaction.

– Motor conduct disorder.

▪ Laterality problems.

▪ Dysgraphia.

▪ Dyspraxia.

▪ Psychomotor instability.

– Behavioural disorders.

▪ Oppositional, defiant, hostile and aggressive behaviour.

▪ Phobias and fears.

▪ Obsessive behaviours and rituals.

▪ Hysterical behaviour.

▪ Attention deficit disorder with hyperactivity.

– Affective disorders.

▪ Depression.

▪ Anguish and anxiety.

– Bladder/bowel control problems.

RETURNING THE INFORMATION:

Once the assessment has been completed, it is necessary to relay the results by means of two procedures:

–       Making a written report.

–       Verbal information to the family and/or the patient.

SETTING GOALS AND THE DEVELOPMENT OF THE INTERVENTION PROGRAMME

Subsequently, the general objectives are established, and the specific initial targets and intervention programme are drafted:

–       Psychological and neuropsychological objectives.

–       Specific cognitive objectives to be developed during Occupational Therapy.

INTERVENTION 

The next step is intervention, rehabilitation and carrying out the appropriate neuropsychological and psychological treatments, using the wide range of psychotherapeutic techniques and procedures available to adults, adolescents and children.

Establishment of guidelines for the management of the patient by the hospital staff and by the family (behaviour modification programmes, as well as programmes to address aggressiveness, severe memory problems, etc.).

FOLLOW-UP

–          Monitoring of cognitive behavioural progress during the therapeutic process.

–          Restructuring of the initial objectives.

–          Drafting of clinical reports on a quarterly basis.

–          Provision of periodic information to the family.

–          Coordination and supervision of occupational therapy.

DISCHARGE

Drafting of clinical reports on treated patients upon discharge, which reflects, in detail, what the psychological or neuropsychological situation is at the point of discharge, as well as establishing certain guidelines.

Duties of the Neurologist

The main objective of the neurologist is to optimize the medical, neurological and behavioural state of the patient.

When the patient is admitted, the neurologist is responsible for initially assess the patient, their background and current situation:

  1. Initial assessment of the patient: Through the neurological examination the site of the injury can be determined in order to help direct the most appropriate treatment.  It also identifies the physical , neurological, cognitive and behavioural defects that impair the functional recovery of the patient as well as their ability to perform specific tasks.
  2. Personal history: The neurologist must know the diseases prior to admission, i.e., medical comorbidities that must be treated. Specifically, hypertension, dyslipidemia, diabetes and heart problems.
  3. Assessment of the current situation of the patient with the aim of preventing complications arising as a result of medication, previous diseases and the brain damage. For example, seizures infections (respiratory and urinary), dehydration, fainting, etc.

On admission the pharmacological treatment is monitored and controlled, both neurological and medical. If necessary, diagnostic tests that help in the diagnosis  (analytical, neuroimaging and neurophysiological) or the opinion of a second specialist are sought when associated pathologies so require.

Each week, the neurorehabilitation team meets in a clinical session to discuss the neurorehabilitation objectives of each patient and the progress and obstacles to achieving these goals (for example: pain, depression, spasticity, extrapyramidal effects, cardiovascular instability or breathing).

At the time of hospital discharge, the neurologist assesses the patient’s medical progress and neurological sequelae in order to issue a medical report together with the neurorehabilitation team.